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For example, reversal of epigenetic silencing of the p21 WAF1/CIP1 cyclin-dependent kinase inhibitor is observed in various cancer cell types and for all HDIs

This helps build up the bodys Vitamin B12 stores

This then necessitates the addition of antioxidants such as vitamin E and ascorbic acid to maintain a stability between the generation of ROS and the readily available defensive antioxidants (Qamar et al., 2023)

KPV: Anti-inflammatory and protects endothelium

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